Determining the best buy among the various antacids requires a knowledgeable chemist. Join our weekly lab-report contest for a chance to win cool prizes! All of these remedies are little more than weak bases that react with and neutralize stomach acid, which is primarily hydrochloric acid, HCl.
The reaction is as follows: The analysis you will perform is called a back-titration and it is described briefly below: In this experiment, the reagents combined are an acid, HCl aq and a base, NaOH aq where the acid is the analyte and the base is the titrant. You will be asked to analyze a product, report the base content, and calculate the relative effectiveness per dollar.
Milk of magnesia magnesium hydroxide, Mg OH 2 is a common antacid, normally sold as a suspension in water, that uses hydroxide ions as the base: Various commercial products are available for the relief of heartburn and indigestion. Begin by preparing a 0. The reaction between the two is as follows: The completion of this reaction can be determined via observation through the use of an indicator.
In the lab report, you should report values obtained from analysis i. Prepare the standardized NaOH aq solution in a A titration is a procedure in which two solutions are introduced to form a reaction that once completed, reaches an identifiable endpoint Murphy,p.
Release the titrant into the analyte solution until the reaction has occurred completely. In part A of this experiment, the concentration of NaOH aq was determined.
From this, the change in molarity between the initial concentration of HCl aq and the moles neutralized will determine the mass of the active ingredient in the antacid that can later prove the effectiveness of antacid brands as buffers. The amount of titrant released from the buret at the endpoint signifies the volume of solution necessary to complete the reaction.
You will participate in a class project to determine the best antacid product per dollar from a group of selected products. Standardization of NaOH Trial 1.
Possible criteria to consider are cost per unit specify which unittablet size, active ingredients, dosage and recommended frequency.
Once cooled, add the indicator Methyl Purple.
Because some active and inactive ingredients in the some brands affect the titration, your values may differ.
Conclusion and Error Analysis: In 3 separate mL Erlenmeyer flasks, pipet 25 mL of 0. The amount of this acid consumed by the antacid is equal to the amount of base in the antacid sample: In your lab notebook, based on the data below, write a brief conclusion stating which brand of antacid you would chose 1 sentence and the criteria you used to make this decision sentences.
Data Summary Part A: This will become apparent when the solution remains a constant pink color. An indicator, phenolthalein, must be added to the analyte solution to make the endpoint visible. Once completed, use the volume of titrant released to calculate the moles of excess HCl aq and determine the mass of CaCO3 s present in the antacid tablet.ANALYSIS OF STOMACH ANTACID TABLETS Teacher Notes This experiment is designed for students working singly or in groups of two.
The overall purpose of this experiment is to determine the effectiveness of two different brands of stomach antacid tablets. The procedure, however, involves a number different processes. Solid State Characterization Pharmaceutical Solid-State Characterization Techniques Accredited Laboratory · Detailed/Accurate Results · Quotes by Ph.D.
Scientist. Analysis of Antacid Tablets John Zhang, Amy Pham, Selena Nguyen, Jennifer Lam, Rebekah Ferrini, Yaritza Dudley This was a report for a similar lab.
[moles of HCl neutralized] for Tums is dollars.
For the CVS tablet, it is dollars per moles neutralized. For Rolaids it is dollars. To do the experiment, an antacid tablet will be dissolved in a known excess amount of acid. The resulting solution will be acidic because the tablet did not provide enough moles of base to completely neutralize the acid.
The solution will be titrated with base of known concentration to determine the amount of acid not neutralized by the tablet. Hot plate Lab scoop or spatula Buret, buret clamp and ring stand antacid tablets both neutralize acid, whether in soil or stomach, and therefore must d.
Calculate the NaOH titre volume [Online Report Sheet Q4]. e. Calculate the molarity of the HCl. [Online Report Sheet Q5]. Use the molarity. EXPERIMENT 6 Bases, Acids and Antacids Record the "active" ingredients for each antacid tablet in your notebook.
Crush each antacid tablet separately (so they will dissolve faster) and add each to a separate mL notebook the composition of each antacid tablet with respect to its active ingredients.
Questions to answer in your .Download